TTC Guide

Fertility by the numbers

Fertility Numbers, and What They Don’t Tell You

Numbers about fertility are easy to find. What almost nobody publishes is what each number does not say. Below, a reproductive medicine specialist lists the figures with their sources — and the limit of each one.

The fertile window (physiology)

24hHow long an egg stays fertilisableStable knowledge

The egg is viable for about 24 hours after ovulation.

What this number does NOT sayTiming sex *on* ovulation day can already be late — it's the sperm that waits.

Source: 生理学 / Physiology

約7日How long sperm survive in the female tractStable knowledge

Sperm can survive around a week in the tubes.

What this number does NOT saySurviving is not the same as staying fully fertile — the days just before ovulation matter most.

Source: 生理学 / Physiology

排卵2日前〜当日The most fertile daysStable knowledge

The fertile window runs from 5 days before ovulation to 1 day after; the peak is the 2 days before ovulation through the day itself.

What this number does NOT sayOvulation shifts between cycles — there is no reliably "safe" day.

Source: 生理学 / Physiology

約14日The luteal phase (ovulation to next period)Stable knowledge

Your period arrives about two weeks after ovulation — so ovulation is ~2 weeks before your next expected period.

What this number does NOT sayThis backward calculation fails if your cycles are irregular.

Source: 生理学 / Physiology

約0.3℃The basal body temperature rise after ovulationStable knowledge

The rise confirms that ovulation happened.

What this number does NOT sayBy the time you see it, the fertile window has closed — BBT cannot predict.

Source: 生理学 / Physiology

Cumulative chance of conceiving

15% → 50% → 80% → 90%Cumulative pregnancy rate at 1, 3, 6 and 12 months (conservative estimate)Stable knowledge

It climbs 30 points between months 3 and 6, but only 10 points between months 6 and 12.

What this number does NOT sayWaiting longer buys much less than people assume — month 6 is the decision point.

Source: 書籍本文 / Book, Fact 17(タイミングを特に合わせない前提の保守的な提示)

38% → 68% → 81% → 92%Cumulative pregnancy rate when ovulation is tracked and sex is timed (1, 3, 6, 12 cycles)Stable knowledge

A German prospective study of 346 couples using natural family planning to time intercourse.

What this number does NOT sayThese figures do not apply to untimed intercourse — the precondition changes the result substantially.

Source: Gnoth C, et al. Hum Reprod. 2003;18(9):1959-66.

約半数Share of couples still not pregnant after 6 well-timed cycles who are subfertile or infertileStable knowledge

This is the evidence behind treating six cycles as the sensible limit for watchful waiting.

What this number does NOT sayThe other half have no identifiable problem — six cycles without success is not itself abnormal.

Source: Gnoth C, et al. Hum Reprod. 2003;18(9):1959-66.

92% / 86-87% / 82%Chance of conceiving within 12 cycles (ages 19–26 / 27–34 / 35–39)Stable knowledge

782 couples across seven European centres, adjusted for timing and frequency of intercourse.

What this number does NOT sayAbsolute sterility stays around 1% at every age. What rises with age is difficulty, not impossibility.

Source: Dunson DB, et al. Obstet Gynecol. 2004;103(1):51-6.

75% / 66% / 44%Share who achieve a live birth within one year of starting (starting at 30 / 35 / 40)Stable knowledge

A model accounting for miscarriage and age-related infertility. Within four years: 91% / 84% / 64%.

What this number does NOT sayART recovers only about half of the births lost by delaying from 30 to 35, and under 30% of those lost from 35 to 40. "We can always do IVF" does not hold.

Source: Leridon H. Hum Reprod. 2004;19(7):1548-53.

21% → 52% → 73% → 95%Pregnancy rate without contraception at 1, 3, 6, 12 months (younger women)Stable knowledge

The twenties are the most fertile years — and therefore the highest-risk years for unintended pregnancy.

What this number does NOT sayThe same number reads as good news or as a warning depending on what you want.

Source: 書籍本文 / Book, Fact 11

1〜4% / 月Monthly natural conception rate once infertility is established (1+ year)Stable knowledge

About 20% even after six more months of trying.

What this number does NOT sayContinuing to "let nature take its course" does not restore the odds — it only spends time.

Source: 書籍本文 / Book, Fact 1

Ovarian reserve (egg quantity)

3〜5 ng/mLTypical AMH in the 20s to early 30sStable knowledge

A marker of how many eggs remain; it approaches zero around menopause (~52).

What this number does NOT sayIt says nothing about egg quality, and varies enormously between women of the same age.

Source: 書籍本文 / Book, Fact 4

1.0 / 2.0 ng/mLThe low-side thresholds used in clinic (1.0 and 2.0 ng/mL)May be updated

Below 1.0 is treated as low; 1.0–2.0 as mildly low. The ESHRE Bologna criteria define diminished reserve as under 1.1 ng/mL.

What this number does NOT sayLow reserve does not mean you cannot conceive — egg quality still tracks your age, not your AMH.

Source: ESHRE Bologna criteria (2011) ほか

20代 4.0 / 30代 2.8 ng/mLAge-specific high-side cut-offs used in PCOS assessment (4.0 in the 20s, 2.8 in the 30s)May be updated

From the JSOG PCOS diagnostic criteria (2024). No high-side判定 is applied from age 40, as the criteria do not specify one.

What this number does NOT sayA high AMH alone does not diagnose PCOS — cycle irregularity, ultrasound findings and hormone levels are all required.

Source: 日本産科婦人科学会 PCOS診断基準 2024 / JSOG PCOS criteria 2024

1〜2 ng/mLAMH at this level in your 20s or early 30s counts as lowStable knowledge

Depending on how many children you hope for, it can justify moving faster.

What this number does NOT sayLow does not mean you cannot conceive, and it does not predict this cycle.

Source: 書籍本文 / Book, 付録3

100人に1人 / 1000人に1人Frequency of premature ovarian insufficiency (under 40 / under 30)Stable knowledge

Eggs run out early — potentially right around the average age of marriage.

What this number does NOT sayThere are no symptoms until reserve is nearly gone; a shifting cycle length is the first clue.

Source: Luborsky JL, et al. Hum Reprod. 2003;18(1):199-206.

25〜38日Textbook range for a normal cycleStable knowledge

Women who conceive smoothly often sit in the 28–32 day range.

What this number does NOT sayA short 25–26 day cycle can signal falling reserve; 35–40 days means ovulation timing varies widely.

Source: 書籍本文 / Book, Fact 6

Success rates in fertility treatment

1〜4% / 周期Timed intercourse, per cycle (under 35)Stable knowledge

Around 20% cumulatively over 3–5 cycles.

What this number does NOT sayEach single cycle fails more than 90% of the time — plan in blocks, not in months.

Source: 書籍本文 / Book, Fact 19

4〜8% / 周期IUI, per cycle (under 35)Stable knowledge

Around 30% cumulatively over 3–5 cycles.

What this number does NOT sayIt only delivers sperm closer — everything after fertilisation is the same as natural conception.

Source: 書籍本文 / Book, Fact 19

20〜30%IVF pregnancy rate per transfer (up to age 30)May be updated

The most effective treatment, and efficient because one retrieval yields several eggs.

What this number does NOT sayIt cannot increase how many eggs you have or improve their quality. Over 40, it falls below 20%.

Source: 日本産科婦人科学会ARTデータ / JSOG ART registry

22〜24mmFollicle diameter just before ovulationStable knowledge

It grows about 2mm a day near ovulation, so ultrasound can pinpoint the day.

What this number does NOT sayThis works even when cycles are irregular or stress delays ovulation.

Source: 書籍本文 / Book, Fact 19

Infection and cancer prevention

10〜20人に1人Chlamydia prevalence in Japanese women in their early 20sMay be updated

A single exposure to an infected partner transmits it 30–50% of the time.

What this number does NOT sayIt is usually silent — untreated, it can block the tubes and cause infertility.

Source: 書籍本文 / Book, Fact 9

生涯50〜80%Lifetime chance a woman acquires HPV through sexStable knowledge

90% clear it naturally within two years.

What this number does NOT sayA minority persists and can progress to cervical cancer over 5–10 years — with no symptoms along the way.

Source: 書籍本文 / Book, Fact 10

年間約1万人 / 約3000人Cervical cancer cases / deaths per year in JapanMay be updated

The second leading cause of cancer death in women aged 25–40 there.

What this number does NOT sayScreening every 1–2 years plus HPV vaccination prevents most of it — these are largely preventable deaths.

Source: 書籍本文 / Book, Fact 10

Contraception

92〜99%Effectiveness of the combined pillStable knowledge

A method a woman controls herself; about ¥4,000/month in Japan.

What this number does NOT sayIt does not prevent STIs — condoms are still needed alongside it.

Source: 書籍本文 / Book, Fact 11

99%以上Effectiveness of an IUDStable knowledge

Around five years of protection from one insertion, with fertility returning immediately after removal.

What this number does NOT sayIt requires a clinic procedure.

Source: 書籍本文 / Book, Fact 11

80〜90%Effectiveness of emergency contraceptionStable knowledge

Must be taken within 72 hours; ¥20,000–30,000 per use in Japan.

What this number does NOT sayNot a routine method — starting the pill in advance is both more reliable and cheaper.

Source: 書籍本文 / Book, Fact 11

Test thresholds

2.5 μIU/mL未満Target TSH when trying to conceiveMay be updated

Keeping it in range lowers miscarriage and preterm birth risk.

What this number does NOT sayThyroid function alone does not explain irregular cycles.

Source: 書籍本文 / Book, 付録3

30 μg/dL以上Target 25-OH vitamin DMay be updated

If deficient, 25–50 µg (1,000–2,000 IU) daily; reported to help cycle regularity and the implantation environment.

What this number does NOT sayFat-soluble and accumulates — do not overdose, and retest after 1–2 months.

Source: 書籍本文 / Book, 付録3

32倍以上Rubella HI antibody titre considered protectiveStable knowledge

Below 1:32, vaccination is recommended before trying.

What this number does NOT sayIt is a live vaccine — avoid pregnancy for 2 months after, and check your partner too.

Source: 書籍本文 / Book, 付録3

A clinician’s own decision rules

These are not guidelines. They are the thresholds the author — a practising reproductive medicine specialist — uses in clinic. Where they deliberately differ from the standard advice, the reasoning is given.

If you are under 30, start testing after 6 months; if you are 30 or older, after 3–6 months

WhyDeliberately earlier than the standard 12-month definition of infertility: months 6–12 add only ~10 points of cumulative pregnancy rate, while egg quality and quantity keep falling throughout.

When cycles shorten to 25–26 days, AMH is often around 0.4–0.5; once cycles stretch to 40–60 days or periods stop for 3+ months, AMH is often below 0.1

WhyAs reserve declines, cycles first shorten and then lengthen. The change in cycle length is the first sign you can notice yourself.

Plan backwards: about 2 years per child — 2 years for one, 4 for two, 6 for three

WhyConception, pregnancy and recovery before the next attempt take roughly two years each. Ideally the family is complete by around 35.

What testing can and cannot reveal

What tests can tell you

  • Whether the tubes are open (HSG / saline scan)
  • Whether motile sperm are present (semen analysis)
  • Whether ovulation happened (mid-luteal progesterone)
  • Roughly how many eggs remain (AMH)

What tests cannot tell you

  • Whether the egg actually entered the tube
  • Whether egg and sperm fertilised
  • Whether the embryo reached blastocyst stage
  • Whether the blastocyst implanted

Timed intercourse and IUI are, by definition, treatments carried out without knowing which step is failing.